Proceedings of the National Academy of Sciences of the United States of America, Vol. 104, No. 5 (Jan. 30, 2007), pp. 1522-1527 (6 pages) Knowing gene structure is vital to understanding gene function ...

Microarrays have been developed that tile the entire nonrepetitive genomes of many different organisms, allowing for the unbiased mapping of active transcription regions or protein binding sites ...

Microarrays, including genome tiling microarrays, are exceptionally powerful tools for querying diverse genomic features, including mapping gene expression and structure, analyzing polymorphisms, ...

This tiling-path array-design approach ensures researchers get the complete picture on genome-wide copy-number changes. Ultrahigh resolution detection of small deletions and amplifications, as well as ...

Array-based comparative genomic hybridization (aCGH) has revealed copy-number variations (CNVs) to be the cause of MR. 6, 7, 8 Although Tarpey et al. 4 screened for mutations in the coding regions of ...