Arsenal, Mikel Arteta
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Both teams are bound to be depleted for this encounter, and Arsenal are set for a fight in Bruges. Plenty have had difficulties at the Jan Breydelstadion over the years, including Barcelona last month, and Arsenal are unlikely to blitz past their opponents on Wednesday.
Take a look back at all the updates from Tuesday's matches in matchday five of the UEFA Women's Champions League.
"I want to play every game - 90 minutes. But I want to help the team and win titles with this football club. Even if I play five minutes, I'm going to try my best, try to win and score and help the team."
Arsenal's players showed a huge range of emotions after conceding late against Aston Villa. What can we learn from them?
Aston Villa beat Arsenal 2-1 at Villa Park on Saturday as Emiliano Buendia won it with the final kick of the game, as Villa moved just three points behind Arsenal in the table. The Premier League title race has been blown wide open.
Arsenal have struggled to live up to their tag as European champions this season, having lost twice already in the newly formatted group stage of the Champions League. This win ensured they jumped up to sixth in the table,
Aston Villa stunned Premier League leaders Arsenal with a dramatic stoppage-time winner today. Matty Cash thumped home at the back post (36') before sub Leandro Trossard equalised from close range (52'). Emi Buendia then curled into the top corner with seconds remaining to give his side a last-gasp victory (90+5').
Arsenal take on Club Brugge in the Champions League as they look to maintain their 100 per cent record in the competition - but that might be easier said than done